Precision and functional specificity in mRNA decay
Yulei Wang, Chih Long Liu, John D. Storey, Robert J. Tibshirani, Daniel Herschlag, and Patrick O. Brown
Yeast mRNA turnover homepage
Figures in the paper
Interactively explore and download the data
Supplemental information
People involved in the project


Global yeast mRNA decay profiles: Two gif images are displayed for each mRNA for its overall decay and PolyA(+) decay profiles. Each profile contains three independent decay timecourses with a best fitted non-linear exponential decay (red solid line) and 95% percentage confidence interval of the fitting (dashed red lines). The estimated half-life and 95% percentage confidence interval are listed at the top of each gif image.

  • Browse the global yeast mRNA decay profiles

  • Search individual mRNA decay profile by either Gene ID or Name.

  • Data in a tabulated format, as well as an off-line searchable browser, are available in the downloads section below.

Correlation between mRNA half-lives and general mRNA features

mRNA Half-life comparison with published data:

Statistical analysis of protein complexes:
  • Methods
  • Results a tabulated table of complexes with coordinated decay rates is available in the downloads section below.


File Size Description
Text 1.0 MB Table in text tab-delimited containing half-life information, with decay constant and 95% confidence interval for overall and Poly-A shortening decay information.
Excel 3.1 MB Table in Excel format containing the raw data for the decay time courses.

12 MB

6 MB
Image Display (version 0.85), an image decay curve browser containing the decay curves of both overall and poly-A shortening data for the yeast genome. This program is based on Microsoft Excel Visual Basic macros; enable macros upon opening the program. This program is compatible only with the Windows 9x/NT/2K operating systems.
Excel 35 Kb Table in Excel format containing tabulated data on complexes with coordinated decay rates.


Home | Figures | Data | Supplement | Authors